Sorbitol 70% for stable formulations with strict COA control of glycol impurities

1/ General introduction to Sorbitol 70%

Sorbitol 70%solution is a non-crystallizing multifunctional polyol, widely used in formulations that require high standards of stability, safety, and sensory performance.

Beyond its role as a sweetening agent, Sorbitol 70% functions as a key formulation base, enabling comprehensive optimization across pharmaceutical, food, and cosmetic applications.

The key differentiation lies in its stringent quality control: Sorbitol 70% is supplied with a Certificate of Analysis (COA) that strictly controls Ethylene glycol ≤ 0.1% and Diethylene glycol ≤ 0.1%, significantly reducing toxicity risks and ensuring the highest safety level for oral and high-consumption products.

This is a critical factor enabling manufacturers to meet increasingly strict regulatory requirements during product registration and commercialization.

2/ Composition of Sorbitol 70%

Sorbitol 70% is an aqueous solution containing:

• Sorbitol (D-glucitol) ≥ 70%
• Purified water

With its polyol structure, Sorbitol provides:

• Effective moisture retention
• High compatibility with a wide range of active ingredients
• Excellent physicochemical stability in solution systems

3/ Key advantages of Sorbitol 70%

Sorbitol 70% is not just a formulation base but a strategic solution for formulation optimization:

Strict impurity control for enhanced safety

• Ethylene glycol ≤ 0.1%
• Diethylene glycol ≤ 0.1%

Enhanced stability in liquid systems

• Prevents recrystallization
• Maintains viscosity and structural consistency over time

Improved sensory profile

• Mild, non-harsh sweetness that balances overall taste
• Enhances user experience and product acceptability

Broad formulation compatibility

• Suitable for sensitive active ingredients
• No adverse interactions

International standards and reliable supply chain

• Complies with USP / EP / BP standards
• Manufactured in EXCiPACT GMP-certified facilities
• Available under GSP / GDP conditions with fast delivery

4/ Applications of Sorbitol 70% in high safety formulations

Sorbitol 70% serves not only as a functional ingredient but also as a risk-control component in formulation design, particularly for products requiring high safety assurance:

In pharmaceutical applications for oral safety control

• Acts as a stable base for syrups and oral solutions
• Reduces the risk of toxic impurity contamination from raw materials
• Suitable for pediatric products and long-term use formulations

In food applications for high-consumption safety

• Used in sugar-free confectionery, beverages, and dietary supplements
• Glycol impurity control helps ensure long-term food safety

In cosmetic and personal care applications for enhanced safety

• Commonly used in oral care products (toothpaste, mouthwash)
• Reduces the risk of impurity absorption through mucosal contact

5/ Commercial products using Sorbitol 70%

6/ Product contact information

For more information about Sorbitol 70% supply, please contact us:

• Nutra Hotline: +84 (0) 834 560 500
• Email: biopharma@biorichpharma.com
• Website: www.biorichpharma.com
• Sample / COA request: Please contact us via email to receive the latest Sample and Certificate of Analysis (COA).