Super Disintegrant in Solid Dosage Forms: Suitable for tablets, capsules, and granules with the following usage levels:
Tablets: Wet granulation: 3% Direct compression: 2%
Capsules: 10–25%
Dispersible tablets: ≥3%
Powders and granules: 1–2%
Improves Disintegration of Poorly Soluble Drugs: Enhances the performance of active ingredients with poor solubility (e.g., Atorvastatin) and tablets with poor disintegration properties (e.g., those containing Dicalcium Phosphate as filler).
Accelerates Active Ingredient Dissolution: Improves the dissolution rate of drugs (e.g., Simvastatin).
Enhances Stability of Moisture-Sensitive Drugs: Increases the stability of actives like Levothyroxine Sodium Hydrate.
Advantages
Manufactured in Gangwal facilities with GMP Excipact certification valid until 2026.
Superior wicking ability compared to Sodium Starch Glycolate and better swelling capability than Crospovidone.
Faster disintegration compared to Sodium Starch Glycolate and Crospovidone.
Enhances solubility and bioavailability of active ingredients.
Does not affect compressibility or flowability.
Effective at low concentrations (0.5–3%).
Compatible with most active ingredients and excipients.
Examples of Commercial Drugs Containing Croscarmellose Sodium
